Dr Art Hister – You Are What Your Mom Ate – or Not

One of the more intriguing pathways being followed by some researchers the last few years is the one that follows along the theory that lots of the health outcomes that we experience as mature adults are actually a function or a result of what happened to us not only 20 or 30 years earlier, that is, in adolescence or early adulthood, but rather that many of the health conditions we develop in midlife and our senior years are actually a consequence of what happened to us in early childhood, even infancy, and perhaps even in utero.

For example, it’s now very well established that the odds of developing osteoporosis in adulthood are highly related to the exercise we do – or that we don’t do – when we’re much younger. The same relationship – what we do or don’t do as kids or even younger leading to disease much later in life – holds for some cancers (breast cancer in adults, for example, has been linked to exercise in our young years, as the risk of melanoma is related to sun exposure in childhood, and others), some cases of high blood pressure and heart disease and strokes, and so on.

Well, according to a fascinating recent study just published in the Proceedings of the National Academy of Sciences, some cases of dementia in adulthood may even be traced to what happened to our moms while we were still in utero.

In this study, the researchers conclude that people who’d been exposed to severe prenatal malnutrition in the Netherlands during World War II (that is, their moms were literally starving while pregnant with them) had significantly higher odds of suffering early cognitive decline in adulthood compared to those who’d not been similarly exposed to malnutrition in utero, that is, people who’d been fetuses carried by moms suffering severe malnutrition during the war were at higher risks of cognitive deficits in midlife than their peers who had been carried by moms who had enough to eat while pregnant.

Just another clear indication why a village raises a child, because when a pregnant woman doesn’t get enough good food to eat, we all pay the costs eventually.

Dr Art Hister – It’s Never Too Late to Change

One of the most important lessons I try to leave with my audiences, especially when I’m addressing a group of seniors, is this: it’s never too late to change and to start doing healthy lifestyle things you’ve long neglected or even never done.

So even when you get into your nineties – and the great thing is that the over-80 demographic is probably the quickest-growing demographic in Canada – there is always something more you can do to make your life more pleasant, to give you more energy, to help you cope with the inevitable conditions that accompany aging, to reduce your risk of illness, to keep your brain sharper, and even perhaps to prolong your life. Although, if you are going to make a change, one other bit of advice: go about it slowly because there’s really no rush.

And to illustrate the truth of that advice, that is, that it really is never too late to make healthy lifestyle changes, a study from Brigham and Women’s Hospital in Boston followed 2231 patients who had what is called left ventricular (LV) dysfunction, that is, in these people, the left ventricle of the heart (the bearing chamber that sends blood into the rest of the body) wasn’t working properly any more as a result of a heart attack.

Of these people, 463 had been smokers at the time of their heart attack, and although most of us would think that none of them would continue to smoke after suffering a heart attack, we know from many studies that a majority of smokers continue to smoke after a heart attack, which was the case in this study, too: 268 of these people continued to smoke.

At the end of 5 years, comparing the smokers with the ones who’d quit, 15 % of the non-smokers had had a 2nd heart attack compared to 23 % of the smokers.

So repeat after me: it’s never too late to quit, to start doing more exercise, to eat better, etc. It just takes will.

Dr Art Hister – Walking For Your Brain

I’m often asked by viewers, readers, listeners, my public forum attendees for: the “best” form of exercise, and to that there’s really only one answer, to wit, the best form of exercise is the form of exercise you will actually do. So, although swimming is a terrific exercise, if you hate water like I do (loathe the stuff, either in me or to lie in it), then there’s really no point in undertaking a swimming program because you’ll quit the 2nd time you realize you have to get wet to swim.

If I had to recommend one form of exercise for a typical large population, however, I would instantly pick walking.

Walking has many benefits: it’s aerobic (or it can be), it’s easy to do anywhere (even in a hotel room or a mall), it can be done inside (on crummy weather days), it’s cheap (if you’re spending a lot on “great” runners, you’re probably wasting a lot of money) , and it’s social (it’s easy to walk with friends).

Plus, regular brisk walking has been linked to multiple health benefits, such as improved brain function, which is nicely illustrated in a study from the University of Illinois (published in Frontiers in Aging Neuroscience), in which researchers took 65 previously sedentary seniors and split them into two groups.

One group was told to do stretching and toning exercise, the others were put into a brisk walking group.

At the end of a year, the “toners” showed no improvement in cognitive scores (compared to when they entered the study) while the brisk walkers had significantly improved cognition scores, and had good improvements in certain measures of brain functioning that were investigated via functional MRIs.

Bottom line: walk more – it’s good for your brain.

Dr Art Hister – Too Much Stress Can Kill You

Finally, a bit of proof.

Everyone out there probably believes – and it’s good old common sense to hold this view – that stress is a killer.

The problem is, however, that it’s very hard to show that link in studies. So, whereas many studies have shown that people who self-report having a lot of excess stress and people who seem to researchers to be under lots of stress have poorer health outcomes, including earlier deaths than people who don’t feel or don’t seem to be under as great a stress burden; those are not the best objective means to evaluate the role that stress plays in these deleterious health outcomes.

In other words, what you need is an objective standard measure of stress load, such as cortisol levels, for example.

And that’s the neat thing about a recent study in the Journal of Clinical Endocrinology and Metabolism (JCEM, thank God).

In this study, researchers measured urinary levels of cortisol, the stress-related hormone, in 861 people over the age of 65, and found that the death rate was directly related to the cortisol level, that is, the higher the cortisol level, the more likely it was that that person would die in the 6 years that the study went on.

And as you’d probably expect, too, elevated cortisol levels were related only to higher rates of death from cardiovascular disease, in other words, from heart attacks and strokes.

London Drugs betterCare – Stress Management

Stress. This one little word carries the weight of the world. And it’s responsible for many health complaints in doctors’ offices across Canada. But what exactly does this word mean? Stress is the “wear and tear” your body experiences as you adjust to the continually changing environment. It has physical and emotional effects and can cause a variety of feelings.

READ MORE

London Drugs betterCare – Osteoporosis

If you have ever wondered why so many elderly people seem to be stooped over and unable to stand up straight, the answer is osteoporosis, a condition in which bones become fragile and break easily. A series of small fractures and compressions in the bones of the spine causes the spine to curve into an “S” shape that makes the person bend forward.

It’s normal to lose some bone material. In fact, throughout our lives our bodies go through a continuing process of losing old bone and making new bone material to replace it. When we are young, the amount of bone material the body makes is greater than the amount it loses, and bone mass (the total amount of bone material in our bodies) increases. In early adulthood the process tends to reach a balance, and our bodies only replace what we actually lose, stabilizing our bone mass. Later, we begin to lose bone faster than we replace it. Over time, this can lead to weaker bones, a condition known as osteoporosis.

As we lose bone mass, all of our bones become fragile, not just the bones in our spine, and they fracture more easily. In fact, in someone with severe osteoporosis, something as simple as a strong hug can break a bone.

A Special Problem for Women

Even though anyone can develop osteoporosis, it occurs far more often in women. There are a number of reasons for this. To begin with, a woman’s bones are generally smaller and lighter than a man’s, so there is less bone mass to lose. Also, men reach their level of peak bone mass later than women, so they have more bone material when they enter the stage when their bone mass stabilizes. And when women go through menopause, their bodies stop making the hormone estrogen, and estrogen plays an important role in preventing bone loss.

In addition to being a woman, there are other factors that increase a person’s risk of osteoporosis. You are more likely to develop it if you are Asian or Caucasian (especially if you are fair-skinned); if you have a small, thin build; or if you have a family history of osteoporosis. Beginning menopause before the age of 45 (either naturally or as the result of having your ovaries removed surgically) also increases risk.

Some lifestyle factors also increase your chances of getting osteoporosis. These include: not getting enough exercise, smoking, consuming too much alcohol or caffeine, and not getting enough calcium. In addition, having certain medical conditions may make you more susceptible to osteoporosis, including diabetes, hyperthyroidism, and anorexia. Taking certain medicines—such as the steroids used to treat asthma and arthritis, certain anticonvulsants, some diuretics, and medicines that contain aluminum—also increases your chances of developing the condition. Taking too high a dose of a prescribed thyroid hormone is another contributing factor. If you aren’t sure if the medicines you take increase your risk, ask your London Drugs pharmacist.

The Telltale Signs

It is unfortunate, but osteoporosis does not announce its appearance with early warning signs. By the time you experience symptoms, your bones will already have become fragile. Once osteoporosis has become advanced, you may notice that you seem to be getting shorter or that your stomach seems to be sticking out. Eventually you may notice that you are developing a stooped posture and a hump may appear on the back just below the neck.

There are some tests that can detect osteoporosis in its early stages. A quick, painless bone density test can detect bone loss long before it would show up on a regular x-ray. And when this test is repeated over time, your doctor can track your rate of bone loss. A woman should have a bone density test performed if she is at least 65 years of age, had a fragility fracture after age 40, has a family history of osteoporosis, or has been on long-term steroid therapy. Future tests can be compared with this reading to help detect bone loss when it occurs.

There are some simple things you can do to reduce your risk of developing osteoporosis or to slow its progress if you catch it in the early stages. These include:

  • Making sure you get enough calcium by eating a healthy, balanced diet. Good sources of calcium include dairy products, nuts, some seafood, and some green vegetables.
  • Being physically active. Exercises such as walking and low-impact aerobics can help bones stay healthy. Check with your doctor before beginning any exercise program.
  • Not smoking.
  • Limiting the amount of alcohol and caffeine you consume.

Living with Osteoporosis

The treatment for osteoporosis involves a combination of healthy lifestyle changes that emphasize diet, exercise, and calcium supplementation. There are medicines available that can help slow down your rate of bone loss and even help replace lost bone. For women who have gone through menopause, hormone replacement therapy (HRT) may be helpful; however, this treatment is not right for every woman. In fact, there are some women who definitely should not be on HRT. You fall into this category if you have ever had breast cancer or cancer involving your reproductive organs, or if you have a blood clotting disorder. Other medications are available as well, and the choice of treatment is an individual one each woman must make
in consultation with her doctor.

If you have osteoporosis, it is important to do everything you can to prevent falls, because falling will lead to broken bones and immobility. Here are some tips that may help:

  • Use a shower stall instead of a bathtub when you have a choice—or equip your bathtub with handrails and be very careful when stepping into or out of the tub.
  • Use handrails whenever they are available in public places such as on stairs or along hallways.
  • Make sure your home is well lit and your walkways are uncluttered.
  • Use elevators instead of stairs or escalators when you have a choice.
  • Wear comfortable shoes that are easy to walk in and stay securely on your feet.
  • Don’t climb on chairs or ladders. If you need help in reaching something, ask someone for assistance.
  • Squat down to pick things up from the floor rather than stooping or bending over, and never try to lift heavy things.
  • When possible, avoid medicines that affect your balance. Your London Drugs pharmacist can tell you whether the medicines you take may have this side effect. If so, there may be another medicine your doctor can prescribe instead.

If you have any questions about osteoporosis or treatments for the condition, please come by the pharmacy and ask your London Drugs pharmacist.

Dr. Art Hister – Osteoporosis

Another new risk factor for osteoporosis to take into account: having suffered a fracture earlier in life.

Osteoporosis is a nasty condition that doesn’t get nearly as much attention in the public sphere – among patients and in the media – as it should.

But osteoporosis not only causes a great deal of disability because of fractures – chronic pain, loss of function, immobility, etc – but it can also kill.

Thus, 20% or so of people who break a hip will die as a direct result of that fracture over the next few months following that fracture.

And osteoporosis is not just an “old woman’s” disease, because men suffer about 1/3 of all hip fractures, and lots of younger people (those not yet seniors) already either have full-fledged osteoporosis or the beginnings of it.

So it’s important to recognize osteoporosis risk factors earlier in life, and to do something about them to lower your chances of ending up with a fracture (or several).

And to that end, we know that smoking, a poor diet, the use of certain drugs, being thin, not doing enough exercise, drinking too much alcohol, a lack of vitamin D, and a diet poor in calcium are all key risk factors for future fractures.

But to that long list you can now add, according to a recent study in the Mayo Clinic Proceedings, having suffered a fracture at an earlier age, that is, according to data from the huge multi-national Global Longitudinal Study of Osteoporosis in Women (GLOW), older women who had fractures when they were young women also had a significantly higher risk of bone fractures later in life, perhaps because those women have some sort of built-in weakness in their bones to begin with.

So, if that’s you, if you’re someone who had a fracture earlier in life, you should be especially careful, I think, to watch your other risk factors for this potentially devastating condition.

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